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14 August, 2019 CellsInvestigationNews

7 out of 10 patients who need a blood-forming cell transplant (bone marrow) do not find a compatible donor in their family, therefore it is necessary to look for this compatibility in unrelated people. Genetic similarity is necessary for the procedure to be successful.

The District Institute of Science, Biotechnology and Innovation in Health IDCBIS, linked to the Health Sector of the Capital District, is carrying out a database of potential donors who could save the lives of patients with diseases such as leukemia, among other serious blood diseases. 

The only way to find a compatible, non-family donor is to have previously identified the genetic characteristics of a population and store them in a database, so that the patient's medical team can search for a possible donor. This database is called the National Registry of Hematopoietic Progenitor Cell Donors.

This type of initiative is already being carried out in other countries such as Japan, New Zealand, the United States and more. In Latin America it has been carried out in Mexico, Argentina, Brazil, Chile and Uruguay. For the first time Colombia will have a donor registry.

Since January 21, 2019, the DarCélulas program began, in which the processes of pre-registration and registration to the Registry were organized, as well as the communication to invite people interested in becoming potential donors in this first stage, subsequently when there is an optimal number of donors, the specialists who attend patients who require a transplant will be able to consult the Registry.  

You may be interested in: First 20 transplants with umbilical cord blood cells donated by Colombian mothers to IDCBIS's Public Cord Blood Bank

In the online pre-registration stage, through the web page www.idcbis.org.co, Colombians can find out much more about the process, as well as schedule an appointment for registration, then to formalize the registration the interested party attends in person at the IDCBIS District Blood Bank where blood samples will be taken to know their genetic information and to register it in the database that is being built. For now the registration process is only available in Bogota.

The resulting database in all registries at international level is available for searches, therefore there have already been successful cases of transplantation in Colombia, thanks to donors registered in other countries. This initiative in our country would give us the possibility of having Colombian donors, with a greater possibility of being compatible with patients in the same territory, since there is a greater possibility of having similar genetic characteristics.

*On August 22nd at 11:00 a.m. the presenter and journalist, Carlos Calero who is a brand ambassador for DarCélulas will attend the IDCBIS District Blood Bank to register for the program and explain to the public the importance of donating blood-forming cells. 


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27 June, 2019 Newsof Blood

The District Blood Bank of the IDCBIS, linked to the Health Sector of the Capital District, makes a priority call for donors of blood group O, Rh + and -, to supply the needs of blood components for patients of the Public Hospital Network of Bogota, since currently there are 1,500 donors of this blood group per month and the need is equivalent to 4,500.

Various factors such as rain, respiratory diseases and mid-year vacations generate a decrease in blood donations and affect the supply of the District Blood Bank IDCBIS, which supplies blood components primarily to public hospitals in the district.
Donations of blood group O - are necessary, since these units are the first to be administered when accidents occur, taking into account that they can be received by people of any other group: A, B, AB and O. On the other hand, there is usually a shortage of O + units, since approximately 50% of the population belongs to this blood group.

The District Institute of Science, Biotechnology and Innovation in Health, IDCBIS, calls on citizens to donate blood. "The blood that is donated does not have a price, it has a value: life itself", says Dr. Bernardo Camacho, director of the Institute, who requests the solidarity of Bogotanos between 18 and 65 years of age in good health and weighing more than 50 kg.

Next weekend the IDCBIS District Blood Bank will be with its mobile units in the following points, waiting for the collaboration of all citizens:

Friday, June 28, 2019

- District Health Secretariat
8:00 a.m. – 4:00 p.m.

- SuperCADE Americas
8:00 a.m. – 4:00 p.m.

Sábado 29 de junio de 2019

- International Charismatic Mission - G12
Cra. 30 with Américas Av.
4 p.m. – 9 p.m.

Sunday, June 30, 2019

- International Charismatic Mission - G12
Cra. 30 with Américas Av.
8:30 a.m. – 4:00 p.m.
- 20 de Julio Church
9:00 a.m. – 5:00 p.m.

– Hospital La Victoria
Dg 39 south # 3-20 east
8:00 a.m. – 2:00 p.m.

Monday, July 1, 2019

- Tunal Park - Entrance 2
9:30 a.m. – 5 p.m.


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21 June, 2019 InvestigationNews

The twentieth unit of umbilical cord blood cells obtained and processed by the Public Cord Blood Bank IDCBIS was transplanted. A new opportunity for a pediatric patient with a severe blood disease in Bogota. This process was carried out thanks to voluntary and altruistic donations from Colombian mothers since 2014 in the capital.

The Public Cord Blood Bank IDCBIS, linked to the Health Sector of the Capital District, has been in charge of selecting donors, as well as collecting, processing, analyzing, storing, typing and distributing hematopoietic progenitor cells in umbilical cord blood units; which are used for the treatment of different diseases that affect the blood, immune system, metabolism or bone marrow; especially in minor patients.

One of the cases was that of Maryuris, a nine-year-old girl from Barranquilla who recovered from medullary aplasia (a condition in which the bone marrow stops producing hematopoietic progenitor cells totally or partially, affecting the production of blood components), at a major pediatric hospital in Bogotá, thanks to a transplant performed with umbilical cord blood cells in 2017, shortly after a life-threatening diagnosis by the treating medical team.

You may be interested in: Research Team of the Public Cord Blood Bank IDCBIS makes important publication in the Scientific Journal Human Immunology

Maternal umbilical cord blood contains cells capable of producing blood components, these are called hematopoietic progenitor cells, which, when transplanted into a patient with a serious blood disease, can generate new blood components. A process similar to sowing a seed capable of creating new plants.

Once the donated cord blood cells are stored and cryopreserved, the amount of hematopoietic progenitor cells in each unit is identified. Eight out of ten units do not have the necessary amount of cells to be used for transplantation.

Since 2014, IDCBIS has collected more than 9300 cord blood units, of which more than 1600 have been made available for transplantation. 20 units of cord blood cells have been a hope for relatives of patients in pediatric units in the country.


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The investigation team of the Public Cord Blood Bank IDCBIS reveals frequencies of genes of the population of Bogota donors important in the compatibility in transplants of blood-forming cells, this was done through the study titled HLA -A, -B, -C, -DRB1 and –DQB1 allele and haplotype frequencies of 1463 umbilical cord blood units typed in high resolution from Bogotá, Colombia, which will appear in the important scientific journal Human Immunology member of the American Society of Histocompatibility and Immunogenetics.

Dr. Ana María Perdomo led the research team that carried out the study through which the frequencies of the HLA (Human Leukocyte Antigen) genetic variants of 1463 umbilical cord blood units stored for unrelated transplantation (without family relationship) were calculated. This means a representative sample of the HLA genes of Colombian children, which is immunologically determinant for the eventual transplantation of umbilical cord blood units.

With the statistical data presented in the study, possible associations between the different HLA variants can be inferred, which is useful for blood-forming cell donor registries in the world, to predict possible compatibilities with patients who have similar genotypes, including the possibility of finding a donor in our country. When there is compatibility between donors and patients, rejection at the time of receiving a transplant is avoided.

First Colombian population study typed with five DNA characteristics

Through the collection of more than 9,300 cord blood units since 2014, with 1666 made available for transplantation by the IDCBIS Public Cord Blood Bank, it has been possible to identify the HLAs corresponding to the 1463 units.

Typing is the process through which HLA identification is made, which was performed on each umbilical cord blood unit. This is the first study that takes into account five DNA characteristics in the Colombian population in order to obtain relevant information for transplants.

You may be interested in: Delegation of researchers from Lazio - Italy visits IDCBIS in search of international cooperation

The study published in the scientific journal Human Immunology allows an approach to the most frequent variants in the genes present in the HLA in the Colombian population. "Knowing more about the genetic characteristics in high resolution of our population, we can contribute to donor search strategies, as well as make transplant processes increase their chances of success in patients who require it," says Dr. Ana Maria Perdomo, IDCBIS researcher.

The Public Cord Blood Bank IDCBIS, linked to the Health Sector of the Capital District, is in charge of selecting donors, as well as collecting, processing, analyzing, storing, typing and distributing umbilical cord blood units, which are used for the treatment of different diseases that affect the blood, immune system, metabolism or bone marrow, especially in underage patients.


Read the article here

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12 March, 2019 NewsAwards

This Tuesday, the District Institute of Science, Biotechnology and Innovation in Health IDCBIS, belonging to the Health Sector, gave the Christian Church El Lugar de su Presencia recognition for its great support to blood donation from its community, with a total of 2753 blood donations in 22 donation days in recent years; this large number of altruistic acts has benefited more than 7,000 patients of the Public Hospital Network in the city of Bogota and other hospital institutions nationwide.

The award was presented by IDCBIS Director Dr. Bernardo Camacho to Pastors Claudia Bermúdez and Orlando Reyes and to representatives Alex Torres and Óscar Ferro, from El Lugar de su Presencia Church, who expressed their gratitude for being able to make these alliances with the Health Sector for the health and wellbeing of the capital's community.



25 January, 2019 CellsNews0

The IDCBIS presents the call for financial support for the development of a master's degree related to the donation of hematopoietic progenitor cells, since one of our functions is to manage lines of research and technological innovation in various fields of human health sciences, with emphasis on transfusion medicine, tissue engineering, advanced therapy and regenerative medicine in coordination with national and international academic and research centers.

Invitation here

In accordance with the above, we attach the call and ratify the dates of the process set forth therein.

If you have any questions, please contact the Innovation and Organizational Development Group:

PBX 3649620 ext. 9468

Stage Dates
Publication of the terms of the call for proposals January 10, 2019
Registration of application documents February 28, 2019
Verification of compliance with minimum requirements March 4, 2019
Evaluation of proposals and interviews and final selection March 5 to 15, 2019
Notification of results March 18, 2019

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25 January, 2019 Uncategorized

The DarCélulas program was born thanks to the project: Establishment and organization of a National Registry of Hematopoietic Progenitor Cells Donors in Colombia, which is developed by the District Institute of Science, Biotechnology and Innovation in Health IDCBIS.

DarCélulas is implemented in order to organize a database to identify people willing to donate their blood-forming cells, which would be transplanted to help patients with severe hematological diseases such as leukemia.

Information and pre-registration are the first two steps that are communicated to those who are interested, this can be done through www.idcbis.org.co/darcelulas. The purpose of these steps is to ensure that people are aware of the process, including the commitments to be assumed, the context and the moments in which the project is to be developed, taking into account that it is still in a pilot phase.

You may be interested in: Management of 2nd degree facial burns with amniotic membrane preserved in 85% glycerol.

The next step will be in March, when people will be able to approach the IDCBIS District Blood Bank to receive more information in person. Once the potential donor expresses certainty of being included, samples are taken to make their respective HLA typing (Human Leukocyte Antigen), which can be used to measure compatibility with a potential patient who in the future and in the implementation stage requires a transplant of blood-forming cells.

The program still needs to complete a few steps before the first donation can be made through the Registry.

How are donations made?

When a person suffers from a blood disease, he/she goes through several processes that the medical staff determines, so it is at the discretion of this staff to resort to a transplant of blood forming cells. When this process is decided, first a search for a compatible donor in the family is made.

About 70% of patients do not find the necessary compatibility in a person of their family, at this moment the National Registry of Hematopoietic Progenitor Cells Donors becomes necessary in order to search for a compatible donor. If the right person is found to make the donation, he/she will be contacted; at this point the process depends on the commitment of the potential donor, since if he/she refuses to make the donation or has not kept his/her contact information updated, it will be necessary to look for another donor, with less possibilities of finding him/her.

Once the compatible donor accepts, they go through a donation process very similar to blood donation by apheresis (in most cases) or hip bone puncture, in order to give their blood-forming cells to the respective applicant; the identities of both are kept secret for security. From experiences in other countries, it is known that donation can take time to be requested and it can take years before a person is contacted after registration.


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23 January, 2019 InvestigationNews
Presentamos el artículo: Manejo de quemaduras faciales de segundo grado con membrana amniótica preservada en glicerol 85% publicado en la revista Cirugía Plástica Ibero-latinoamericana en el volumen 44 número 4, elaborado por el Dr. Jorge Luis Gaviria, Dra. Viviana Gómez y la Dra. Linda Guerrero. Este artículo presenta la experiencia del uso de la membrana amniótica preservada en glicerol como apósito biológico temporal en el tratamiento de quemaduras faciales de segundo grado, superficial y profundo.

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12 October, 2018 NewsAwards
The projects selected are:
1. Evaluation of the supporting capacity of mesenchymal stem cells from different tissues in the expansion of cord blood hematopoietic progenitor cells. Investigator: Dr. Ximena Bonilla 
 
2. Design and evaluation of skin substitutes generated from biological scaffolds and Wharton's Jelly mesenchymal stromal cells for the repair of chronic skin ulcers.Investigator: Dr. Ingrid Silva


Logo a color IDCBIS Centro de investigación reconocido por minciencias r-1763-2021

PASIÓN POR LA CIENCIA Y LA VIDA



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