Statement 1.
Call for Financial Support for Doctoral Student Related to Hematopoietic Progenitor Cell Donation and Transplantation in Colombia
Statement 1.
Call for Financial Support for Doctoral Student Related to Hematopoietic Progenitor Cell Donation and Transplantation in Colombia
Continuing with the exercise of the continuous search for international scientific cooperation and thus strengthen knowledge networks with experts in different areas of knowledge, we have received the delegation of the mission of Lazio - Italy in Bogota, who learned firsthand the research capabilities and projects led by IDCBIS.
These initiatives are possible because the IDCBIS is registered as a flagship project of Bogota and is part of the Biopolo area of the Smart Specialization Strategy of the Bogota Chamber of Commerce.
The Smart Specialization of the Bogota Region is an integrated agenda for productive development built collectively for the transformation of Bogota and Cundinamarca based on knowledge and innovation. A dynamic strategy that responds to regional capabilities and international trends for the generation of projects.
Five areas were prioritized for its implementation, made up of a set of productive activities, some of them consolidated and others barely emerging: Bogota Creative Region, Bio-pole, Business Services, Advanced Knowledge HUB and Sustainable City Region.
The IDCBIS is part of the group called Bio-pole, which refers to the development of life sciences, including technologies and productive activities pertaining to agriculture and agro-industry, fine chemistry and health.
Bogotá D. C., August 13, 2018. The District Tissue Bank of the District Institute of Science, Biotechnology and Innovation in Health -IDCBIS-, linked to the District Health Secretariat, has 70,000 cm2 available to benefit the most vulnerable population that has suffered burns by flame, boiling liquid, acid and electricity.
Considering that stem cell transplantation for blood diseases depends on several factors including the patient, the disease, the compatibility and the source of stem cells used, it is important to investigate the factors of the collection, isolation, freezing and thawing process to which these cells are subjected.
For the success of a stem cell transplant it is necessary firstly to have compatibility between donor and recipient, secondly it is necessary that the cells are sufficient according to the patient's weight and that they are in good condition after thawing (living stem cells).
The IDCBIS Public Cord Blood Bank with a scientific approach has been analyzing different variables that may allow improving the processes or identifying characteristics of the cord blood units that allow predicting the success of the transplant.
The umbilical cord blood units collected from altruistic donors in the district are processed in the bank until they are frozen for storage, performing analysis on tissue compatibility molecules, among other analyses.
The finding was awarded by the scientific committee of 16th International Cord Blood Symposium was that removing red blood cells from cord blood units could improve the quality of stem cells for transplantation.
The committee also considered very novel the finding that certain genetic variants present in donors predispose to a better or worse quality of cord blood units, which would allow to choose them before transplantation and avoid transplant failures.
These results were presented by IDCBIS researchers, Dr. Ana María Perdomo Arciniegas and Dr. Diana Vanegas, who represented the Bank's group of researchers, presented the research and resolved the concerns of the most important scientists in the area.
The IDCBIS District Blood Bank offers the service of irradiation of blood components, which consists of a treatment that is done by gamma radiation to red blood cells, platelets, single platelet concentrates (CUPs) and plasma, in order to inactivate the T lymphocytes present in these blood components and prevent Graft Vs. Host Disease (GVHD) in the recipient.
Optimal applications for the use of gamma irradiation are:
-Bone marrow transplant patients
-Patients with Hodgkin's disease
-Neonatal transfusion
-Immunosuppressed patients.
-Oncology patients
The IDCBIS District Blood Bank is the only one with specialized equipment for the irradiation of blood components and tissues using gamma irradiation with Cesium-137 with an optimal distribution of the dose throughout the blood component, which ensures that T lymphocytes do not proliferate.
The blood component irradiation service is provided 24 hours a day, 365 days a year to public and private institutions in Colombia.
The IDCBIS immunohematology laboratory performs the processing of the tests established by current legislation for blood donor samples and apheresis in fully automated platforms favoring a simple, fast, reliable and safe set-up.
Immunohematology referral service to all public institutions in the District and private institutions:
-Resolution of erythrocyte compatibilization cases.
-Extended studies for the diagnosis of autoimmune hemolytic anemia
-Support studies for the diagnosis and prevention of hemolytic disease of the fetus and newborn.
Tests for the identification of irregular antibodies, including allogeneic adsorption techniques, differential adsorption, differential adsorption with enzyme-treated red blood cells, among others.
It also has specialized professionals with extensive experience in the area, with postgraduate degrees and teaching experience, which has positioned the service as a training center for immunohematology with a clinical approach for residents of hematology, pediatric and adult hemato-oncology programs of the National University of Colombia and the University Foundation of Health Sciences - FUCS.
His research activities include the implementation of erythrocyte genotyping techniques, registration of donors with rare phenotypes and study of blood group system frequencies.
The Immunohematology service is provided 24 hours a day, 365 days a year to public and private institutions in Colombia.
IDCBIS will be presenting the Abstract "Tissue Engineered Constructs Based on Mesenchymal Stromal Cells and Acellular Dermis induce the Release of Repair Factors for Cutaneous Lesions "at the 5th World Congress of the Tissue Engineering and Regenerative Medicine in Tokyo -Japan #Termis2018. This is a great recognition to the research work of Dr. Gustavo Salguero, Dr. Ingrid Silva and the entire team of the Advanced Therapies Unit.
The IDCBIS National Registry of Hematopoietic Progenitor Cells Donors project team conducted a referral at INCUCAI, the agency that promotes, regulates, coordinates and oversees organ, tissue and cell donation and transplantation activities in Argentina.
Its main application is in burned patients, the patient when attacked by acid or by any substance that generates burns, loses its major defense which is the skin and is exposed to infections.
The donation of amniotic membrane, which is the placenta itself and comes from pregnant mothers with prior informed consent. Amniotic membrane is usually a biosecure tissue that undergoes cremation,
our goal is to avoid it and take the amniotic membrane, which has many benefits, at the IDCBIS District Tissue Bank, we are optimizing it for patients with burns, ophthalmologic injuries, etc., and we are using it for the treatment of patients who are in need of treatment.
(corneal lesions) and we are about to publish its application for dentistry with different oral mucosal lesions, its uses are multiple.
By donating the membrane you help thousands of patients to improve their quality of life.